THE ACTIVITY CHANGES OF ALKALINE PHOSPHATASE AND ITS ULTRASTRUCTUAL LOCALIZATION DURING LIVER REGENERATION IN RATS
- VernacularTitle:大鼠肝再生过程中碱性磷酸酶活性变化及其超微细胞化学研究
- Author:
Jinting LI
;
Junli WANG
;
Shungang FU
;
Xiaoying LI
;
Kexue MA
;
Cunshuan XU
- Publication Type:Journal Article
- Keywords:
Liver regeneration;
Alkaline phosphatase(AKP);
Cytochemistry position;
Non-denatured electrophoresis
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of AKP activity and its cytochemistry position during liver regeneration following partial hepatectomy. Methods Using colorimetry to analyze AKP activity; using non-denatured electrophoresis technique to analyze the kinds and activity of AKP; using electron microscope cytochemistry to analyze its position. Results During liver regeneration, AKP activity had two peaks at 16*!h and 19*!h and followed by decline dramatically; Three hepatic-derived AKP isoenzymes were detected, and 180*!kD AKP appeared only in liver regeneration; AKP appeared in different part with the process of liver regeneraion.Conclusion AKP plays an important role in liver regeneration and it may involve in cell metabolism, material transportation, DNA synthesis and cell differentation.
