Expression of cystic fibrosis transmembrane conductance regulator in human endometrium
- VernacularTitle:囊性纤维化跨膜转导调节因子在子宫内膜中表达的变化及其意义
- Author:
Xiaoying ZHENG
;
Guian CHEN
;
Haiyan WANG
- Publication Type:Journal Article
- Keywords:
Cystic fibrosis transmembrane conductance regulator;
Endometrium;
Chloride channels
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study expression of cystic fibrosis transmembrane conductance regulator (CFTR) in human endometrium. Methods The expression of CFTR mRNA and protein from 50 samples of normal cyclic human endometrium was examined by in situ hybridization, immunohistochemistry and Western blotting respectively. Results CFTR mRNA and protein expressions were only detected in the endometrial glandular cells with cyclic changes. CFTR mRNA could be detected from the midproliferative phase with the highest level found in the late proliferative phase, significantly higher than those of late-secretory phase endometrium ( P
