To demonstrate the change in peripheral blood T lymphocyte subgroups and cytokines of Behet′s syndrome
- VernacularTitle:白塞病患者血清T淋巴细胞亚群和细胞因子变化初探
- Author:
Shulin SONG
;
Dongmin BI
;
Dongbao ZHAO
;
Xinghai HAN
- Publication Type:Journal Article
- Keywords:
Beh?et′s syndrome;
T lymphocyte subsets;
Cytokines
- From:
Chinese Journal of Rheumatology
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To demonstrate the change in peripheral blood T lymphocyte subgroup and cytokines of Beh?et′s disease (BD). Methods T lymphocyte subgroup was detected by flow cytometry and serum interleukin (IL)-8, sIL-2R, IL-1?, IL-2, IL-6 and TNF-? were assayed by RIA. Results CD4, CD4/CD8, NK of BD decreased evidently and CD8 incrdased. Serum IL-8, sIL-2R increased compared to normal controls. Change of IL-2, IL-6, tumor necrosing factor (TNF)-? , IL-1? showed no statistical significance compared to normal group. Conclusion Change in peripheral blood T lymphocyte subgroup and serum IL-8, sIL-2R can be one of the activity index of BD.
