Sclerosing polycystic adenosis of salivary gland:a clinicopathologic analysis of 2 cases and review of literature

VernacularTitle:腮腺硬化性多囊性腺病二例临床病理观察及文献复习
Author: Minliang JIANG ; Kunkun SUN ; Hongqi SHI ; Saiying ZHU
Publication Type:Journal Article
Keywords: Parotid neoplasms; Parotid Sclerosing polycystic adenosis; Diagnosis
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(8):1162-1164,后插2
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinicopathologic features of sclerosing polycystic adenosis(SPA)of salivary gland.Methods The clinical and pathologic profiles of 2 SPA cases were evaluated.Immunohistochemical study was performed on fixed tissues.The biologic behavior was analyzed with follow-up data.Results The main clinical manifestation of patients was parotid painless nodules.Histological features were embedded cystic dilatation of ducts and alveoli as hyaline sclerosis collagen tissue background,catheter see apocrine metaplasia,focal areas of ductal epithelial hyperplasia and dysplasia.Immunohistochemical staining for calponin and SMA staining showed that the catheter had a layer of myoepithelial cells.Conclusion Sclerosing polycystic sialadenopathy of parotid is a rare disease,the cause and course of the disease are not very clear,but the literature reports are atypical ductal epithelial remarkable phenomenon,thus strengthen the follow-up to patients.