Use of computed tomography in evaluating prognosis for infants with hypoxic ischemic encepholopathy
- VernacularTitle:CT检查对新生儿缺氧缺血性脑病预后判断的价值
- Author:
Lei BAO
;
Jialin YU
;
Tianhe XU
- Publication Type:Journal Article
- Keywords:
Hypoxia,ischemia,brain;
Tomography,X-ray computed;
Infant,newborn;
Pragnosis
- From:
Chinese Journal of General Practitioners
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study computed tomography (CT) in evaluating prognosis for hypoxic ischemic encephalopathy (HIE) in infants. Methods Eighty-five infants diagnosed as HIE underwent CT one week,two months,three to six months and one to one and a half years after birth,respectively. At the same time,neonatal behavior neurological assessment (NBNA) was made at 12 to 14 days after birth. Development quotient (DQ) was used to evaluate their prognosis at age of 1 to 1.5 years. Results Rate of poor prognosis was 40.9% (9/22) in the infants with severe HIE by CT and 5.7% (3/52) in those with moderate HIE within one week after birth. Rate of poor prognosis was 60.0% in the infants with abnormal CT at age of two months. There was no significant difference in their prognosis for infants of moderate HIE with NBNA scores greater than or equal to 35 and less than 35,12 to 14 days after birth. And,72.7% (8/11) of the infants with severe HIE by CT with NBNA less than 35 showed little recovery at 12th-14th days after birth. Conclusions Combination of CT and clinical follow-up with NBNA score one month after birth could play an important role in the evaluation for therapy regime,length of treatment and prognosis in the infants with HIE.
