Study on the endothelial nitric oxide synthase gene polymorphism in Chinese han nationality
- VernacularTitle:中国汉族人内皮细胞型一氧化氮合酶基因多态性研究
- Author:
Fengjin GUO
- Publication Type:Journal Article
- Keywords:
Endothelial nitric oxide synthase;
Gene polymorphism;
Allele;
Genotype
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).The size of PCR fragments ranged from 144 to 188bp containing 19～41 CA repeats and the frequency of (CA)n ranged from 0.34%～14.1%.The heterozygosity(H) and polymorphism information content(PIC) were 0.85 and 0.83 respectively.Significant differences were found in frequencies of eleven alleles including 22-repeats,23-repeats,26-repeats,27-repeats,28-repeats,30-repeats,31-repeats,32-repeats,33-repeats,34-repeats and 35-repeats between Chinese and Caucasians.Conclusion:This site is referred to as a genetic marker with high polymorphism information content.And the distribution of this genetic marker is different in different ethnic groups.
