The study of Lonicera extract from water solution on ovalbumin-induced allergic mice model
- VernacularTitle:金银花水提物对卵清蛋白致敏小鼠的抗过敏作用研究
- Author:
Fei LI
- Publication Type:Journal Article
- Keywords:
Lonicera;
Food allergy;
Immediate hypersensitivity;
Ovalbumin
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of the Lonicera on immediate hypersensitiviy,and to provide pharmacological clues for the further clinical practice.Methods:The effects of Lonicera on both the heat-unstable PCA and the heat-stable PCA experiments of the mice were observed,and the changes of the histamine levels in the ovalbumin-induced allergic mouse's intestines after administrating the Lonicera were detected by observing the histopathologic changes with either HE stain or toludine blue stain and measuring the levels of histamine in the intestines with a fluorescent method.Results:The high and the middle coneatracions of the Lonicera could inhibit the heat-unstable PCA activity in the mice( P 0.05).The high and middle concentracions of the Lonicera were significantly effective,in increasing the percentage of the intact intestinal mast cells( P
