An experimental study on the expression of TNF-? in myocardial injury during stress
- VernacularTitle:TNF-?在小鼠心肌应激性损伤中表达的实验研究
- Author:
Shixiong DENG
- Publication Type:Journal Article
- Keywords:
TNF-?;
ISO;
Myocardium injury;
Immunohistochemical method
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To detect TNF-? in the tissue of myocardium injury during stress and discuss its significance.Methods:To establish a model of myocardium lesion by injecting ISO to mice abdominal cavity,then TNF-? in the tissue of heart was assessed by immunohistochemical method of SP and HE staining in paraffin sections.Results:There were little positive substance of TNF-? expressed in heart in normal control.The positive substance of TNF-? increased significantly after stress.Conclusion:Increase in the expression of TNF-? in stress indicate its participation in the process of myocardium injury,and it may be an objective marker for evaluation of myocardium injury.
