Determination of Constituents of Liuwei Dihuang Wan Migrating to Blood
- VernacularTitle:六味地黄丸血中移行成分的含量测定
- Author:
Ning ZHANG
;
Xijun WANG
- Publication Type:Journal Article
- Keywords:
Liuwei Dihuang Wan;
Fingerprint;
Constituents migrating to blood;
Loganin;
Paeonol
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the content of two original constituents of Liuwei Dihuang Wan migrating to blood. Methods HPLC- fingerprint of the preparation and drug- containing serum fingerprint were established by RP- HPLC. Based on the fingerprints, the original constituents migrating to blood were identified and determined by comparing with the standard. Results Loganin and paeonol were identified as the original constituents migrating to blood; the loganin content was 0.93? 0.01 mg/g and the paeonol was 0.37? 0.01 mg/g. Conclusion Using the constituent content migrating to blood as the parameter, this method will provide scientific evidence for improving the quality control of Liuwei Dihuang Wan.
