Preparation of solid lipid nanoparticles containing volatile oil of Lignum dalbergia odoriferae
- VernacularTitle:降香挥发油固体脂质纳米粒的制备
- Author:
Jing HAN
;
Xing TANG
;
Dechun BA
- Publication Type:Journal Article
- Keywords:
volatile oil of lignum dalbergia odoriferae;
solid lipid nanoparticle;
sonication;
entrapment efficiency
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To delevop new drug delivery system for volatile oil of lignum dalbergia odoriferae and to improve its effect. METHODS: Solid-lipid-nanopaticals were prepared by hot-dispersiom technique and treated further by sonication; the contents of dispersion and entrapment efficiency of nanoparticles were determined by HPLC. RESULTS: Solid lipid nanoparticles containing volatile oil of lignum dalbergia odoriferae was spherelike; The partical size was 40.0nm; the content of dispersion was 72.1%; entrapment efficiency of nanoparticles was 91.27%. CONCLUSION: Solid-lipid-nanopatical may be a suitable drug delivery system for volatile oil of lignum dalbergia odoriferae.
