AN IMMUNOHISTOCHEMICAL STUDY ON TROPIC 1808 GENE EXPRESSIONAL PROTEIN IN THE LESIONED SCIATIC NERVE
- VernacularTitle:周围神经损伤后Tropic 1808基因表达蛋白的免疫组织化学研究
- Author:
Xue CHEN
;
Peiyun ZHANG
;
Xiaodong WANG
;
Jian WU
- Publication Type:Journal Article
- Keywords:
Tropic 1808 gene expressional protein;
Sciatic nerve;
Immunohistochemistry;
Rat
- From:
Acta Anatomica Sinica
1955;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression and the distribution of Tropic 1808 gene expressional protein in the lesioned sciatic nerves of adult SD rats. Methods Both distal and proximal segments of 12 days cut-off sciatic nerves of SD rats were obtained.Then immunohistochemistry and dual fluorescent-immunohistochemistry were performed to observe the expression of Tropic 1808 gene expressional protein in the lesioned sciatic nerves.The positive intensity and area of immuno-response were detected by the image analyses system. Results The Schwann cells's membranes which in the distal and proximal of lesioned sciatic nerves appeared to have positive expression of Tropic 1808 gene expressional protein.The positive intensity and area of immuno-response in the distal end were denser and larger than those in the proximal.Conclusion Tropic1808 gene expressional protein expresses in the Schwann cell's membranes of the distal and the proximal after the peripheral nerves were injured.The positive expression in the distal was higher than that in the proximal.;
