Study on transdermal absorption of baicalin per various kinds of animal skin
- VernacularTitle:黄芩苷渗透不同动物皮肤的透皮吸收研究
- Author:
Qiang LIU
;
Zhiping LU
;
Hongxia ZHU
- Publication Type:Journal Article
- Keywords:
Baicalin Emplastrum;
baicalin;
transdermal administration;
skin
- From:
Chinese Traditional and Herbal Drugs
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectTo study comparatively the transdermal absorption of baicalin per five kinds of animal skin. Methods Improved Franz-call was used for the transdermal study, and the transdermal speed constants of baicalin per five kinds of animal skin were compared. Results The transdermal speed constants of baicalin per skin of mice, hairless mice, rabbits, rats, human are (67.31?23.66), (78.35?3.29), (117.35?29.48), (86.25?7.55), and (84.43?11.27) ?g/(cm2?h), respectively. Conclusion The transdermal absorption of baicalin per skin of hairless mice is more similar to that of human skin.
