Establishment of atrial septal defect model in animal with the Brokenbrough needle via femoral vein
- VernacularTitle:经静脉房间隔穿刺法建立房间隔缺损动物模型
- Author:
Shengqiang WANG
;
Yongwen QIN
;
Jianqiang HU
- Publication Type:Journal Article
- Keywords:
Atrial septal defect;
Balloon dilatation;
Canine
- From:
Journal of Interventional Radiology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the novel method to establish animal model of controllable sized atrial septal defect. Methods Fourteen dogs of both sexes were selected,with weight ranging from 15 to 20kg. Under guidance of fluoroscopy,ASD was established by using Brokenbrough needle and balloon dilatation. Results Tow dogs died of cardiac tamponade.Other twelve dogs had ASD created successfully without complication. Conclusion The method has the advantages of easy manipulation , size controllable and small amount of fluoroscopy exposure.
