Experimental study on regulation of bile duct motility by gastrointestinal migrating motor complex
- VernacularTitle:消化间期移行性复合运动对胆道调节作用的实验研究
- Author:
Li WANG
;
Lei DONG
;
Yanqin QIU
- Publication Type:Journal Article
- Keywords:
Antrum;
Duodenum;
Gallbladder;
Sphincter of Oddi;
Migrating motor complex
- From:
Chinese Journal of Digestion
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective In order to elucidate the mechanism of migrating motor complex (MMC) in prophylaxis and treatment of cholelithiasis,the relationship and interaction between MMC and the bile duct motility were investigated. Methods Forty five adult guinea pigs were allocated into three groups with 15 each. The guinea pigs in control,prucalopride and dibazol groups were fed with saline (0.15 ml/100 g),prucalopride (0.01 mg/100 g) or dibazol (0.6 mg/100 g),respectively. The myoelectrical activities of antrum,duodenum,gallbladder(GB) and sphincter of Oddi(SO) of guinea pigs were recorded simultaneously before and after administration via implanted silver electrodes of the muscle layer. Results Positive correlation in frequency and strength of spontaneous myoelectrical activity was demonstrated among antrum,duodenum,GB and SO before administration( P
