The effect of 17?-estradiol and its metabolites on hepatic stellate cells in rats
- VernacularTitle:17?-雌二醇及代谢产物对大鼠肝星状细胞功能的影响
- Author:
Qinghua LIU
;
Dingguo LI
;
Chunhua ZONG
- Publication Type:Journal Article
- Keywords:
Estradiol;
Metabolism;
Hepatic stellate cell;
Hepatic fibrosis
- From:
Chinese Journal of Digestion
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
?-Est. Besides,?-Est could promote the expression of ER ? by HSC at the concentration of 10 -7 mol/L but not its metabolites. Conclusion The present results indicate that ?-Est may attenuate hepatic fibrosis and the possible mechanism is via the action of its metabolites.
