Changes of nitric oxide synthase and gastrin of Helicobacter pylori infection in duodenal ulcer
- VernacularTitle:幽门螺杆菌感染对十二指肠溃疡患者血清胃泌素、一氧化氮合酶影响的研究
- Author:
Zhiqun WANG
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Nitric oxide synthase;
Gastrin;
Triple therapy
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the important relations between Helicobacter pylori (H.pylori) infection and serum gastrin level and nitric oxide synthase (NOS) activity in order to look for a method treating diseases associated with H.pylori.Methods:Before and after triple therapy against H.pylori with omeprazole 20mg twice a day,clarithromycin 0.25,and metronidazole 0.2 3 times a day for two weeks,fifty-nine with active DU and H.pylori positive,and 39 cases with non-ulcer dyspepsia as control were determined for NOS activity of gastric mucosa and fast serum gastrin level.Results:Patients with DU activity and H. pylori infection,before treatment,had an increased in NOS activity of gastric mucosa and fast serum gastrin level than those after treatment and the control,there were great importance( P
