The influence of acute intoxication of acephate on some antioxydant enzymes in rabbit’s blood red cells
- Author:
Nguyen Thi Muoi
- Publication Type:Journal Article
- Keywords:
Acephate
- MeSH:
Organothiophosphorus Compounds;
Poisoning;
Enzymes
- From:Journal of Practical Medicine
2003;463(10):77-79
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Acephate with dose of oral 100mg/kilo weigh for 1 time made acute intoxication in rabbits and changes in activity clearly with some parameters: plasma ChE enzyme activity reduce about 41% after 3 to 6 hours intoxication, ability recover after 24 hours but after 48hours still hasn’t get medium level. MetHb rate increase highest at 6 hours and after reduce gradually to nomal level at 48 hours. There have change in acid-base balance, rabbits on infect alkali breathing at 3 hours, transform acid poisoning at 6 hours and infect combine alkali at 24hours and 48hours. Erythrocyte SOD enzyme activity reduce. Urea, glucoza, uric acid level increase significant after 3-6hours intoxication and back to normal nearly after 48hours
