In-Vitro Inhibitory Effect of Oleum Curcumae Aromaticae on Leukemia Cell Strain
- VernacularTitle:莪术油对白血病细胞株的体外抑制作用
- Author:
Hong ZHOU
;
Hai SUN
;
Yi ZHONG
- Publication Type:Journal Article
- Keywords:
CURUMA ZEDOARIA/pharmacology;
OLEUM CURCUMAE AROMATICAE/pharmacology;
LEUKEMIA/TCD therapy;
HL - 60 CELLS/drug effects;
K562 CELLS/drug effects
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To evaluate the therapeutic effect of Oleum Curcumae Aromaticae (OCA) on leukemia cell strain HL-60 and K562 by observing its sensitivity in inhibiting HL-60 and K562. [Methods] Subculture of HL-60 and K562 cells was performed on the 96-hole culture plate and OCA 100?L at the final concentration of 400, 200, 100 and 50mg/L respectively was added. The blank control was added with RPMI-1640 culture fluid. After 24, 48 and 72 hours of treatment, MTF 10?L (5mg/mL) was added and the inhibitory rate on the cells was assayed by detecting the absorption value at 570nm wavelength. [Results] The inhibitory effect of OCA on HL-60 and K562 increased with the treatment time. The difference of inhibitory rates 24, 48 and 72 hours after treatment were significant (P
