Studies on Extracting Process of Hujin Granules
- VernacularTitle:虎金颗粒剂提取工艺的研究
- Author:
Qishan LUO
;
Zhaosheng HUANG
;
Zhendong ZHAO
;
Zongwei WANG
;
Yi CHENG
;
Xiaofeng XU
- Publication Type:Journal Article
- Keywords:
HUJIN GRANULES/isolation and purification;
TECHNOLOGY, PHARMACEUTICAL;
RESEARCH DESIGN
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To optimize the conditions of the extracting process of Hujin Granules. [Methods] The orthogonal design was applied. With the total emodin and the total anthraquinone (TA) content as the parameters for the alcohol-extraction, the concentration of alcohol, the volume of solvent and the extracting time were used for optimization of alcohol-extraction. With the total polysaccharide (TP) as the parameters for water-extraction, the soaking time, the volume of water and the extracting time were used for optimization of water-extraction. [Results] The optimum conditions of alcohol-extraction were: extracting with 70% alcohol 245 mL for 2 hours and extracting twice. The optimum conditions of water-extraction were: extracting with 80 mL water (not for soaking) for 1.5 hours, extracting 3 times. [Conclusion] The results indicate that the extracting process is rational and feasible, and can provide evidence for the extracting process of Hujin Granules.