Comparative analysis of the diagnosis criteria for idiopathic inflammatory myopathy subtypes
10.3760/cma.j.issn.1007-7480.2013.09.010
- VernacularTitle:特发性炎性肌病分型诊断标准的比较分析
- Author:
Qian QIAN
;
Na LI
;
Hongrui SHEN
;
Zhe ZHAO
;
Qi BING
;
Nan LI
;
Jing HU
- Publication Type:Journal Article
- Keywords:
Moysitis;
Diagnosis;
Dermatomyositis;
Polymyositis
- From:
Chinese Journal of Rheumatology
2013;17(9):620-622,封3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the consistency between the diagnostic criteria for dermatomyositis (DM) and polymyositis (PM) developed by Bohan and Peter criteria (B/P criteria) and ENMC criteria.Methods The clinical,laboratory and pathological data from 86 patients who were initially diagnosed with idiopathic inflammatory myopathy were collected retrospectively.These patients were diagnosed according to B/P criteria and ENMC criteria,and the similarities and differences between these two criteria were compared.The data were analyzed with Mann Whitney U test and Kappa test by SPSS 13.0 software.Results Thirtyseven DM and 49 PM were diagnosed using B/P criteria.Forty-six DM and 14 PM were diagnosed using ENMC criteria,and 1 was diagnosed as eosinophilic myositis,9 were diagnosed as sporadic inclusion body myositis (sIBM),11 cases were diagnosed as limb-girdle muscular dystrophy type 2B,and the diagnosis of 5 patients could not be clarified.Agreement for DM between these two sets of criteria was very good by Kappa test (κ=0.79),but the corresponding between the two tests for PM was poor (κ=0.26).Conclusion Our study has demonstrated that B/P criteria may cause over-diagnosis and misdiagnosing for PM.ENMC criteria involves immunohistochemical pathology,stratified clinical and pathological exclusion criteria.The diagnostic accuracy of ENMC criteria is much improved.
