EXPRESSION AND CORRELATED SIGNIFICANCE OF INDUCIBLE NITRIC OXIDE SYNTHASE AND p53,BAX IN BENIGN AND MALIGNANT DISEASES OF GALLBLADDER
- VernacularTitle:诱导型NOS与p53、Bax蛋白在胆囊良恶性病变中的表达及相关意义
- Author:
Tianrong REN
;
Ming ZHANG
;
Youfa ZHU
;
Guoliang REN
;
Xiaoqing CHEN
;
Jianwei PAN
;
Guoping REN
- Publication Type:Journal Article
- Keywords:
Disease of gallbladder;
Nitric oxide synthase;
p53;
Bax;
Immunohistochemictry
- From:
Acta Anatomica Sinica
1954;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the expression and correlated significance of inducible nitric oxide synthase and p53,Bax in benign and malignant diseases of gallbladder. Methods In 16 cases of chronic cholecystitis,11cases of chronic cholecystitis with adenomyoma and 24 cases of gallbladder adenocarcinoma,the expression of iNOS,p53 and Bax in gallbladder's wall was detected by SP immunohistochemistry. Results 1^Inducible NOS and Bax expressed in both benign and maligmant diseased gallbladders' wall,compared with benign diseased gallbladders,the expression of iNOS and Bax in adenocarcinoma was decreased(P
