Therapeutical effects of salvianolic acid B on myocardial infarction in dogs
- VernacularTitle:丹酚酸B对犬心肌梗死的治疗作用
- Author:
Lin LI
;
Lisha SUN
;
Jiangping XU
- Publication Type:Journal Article
- Keywords:
salvianolic acid B;
myocardial infarction: myocardial ischemia: lactatedehydrogenase;
epicardial electrocardiogram
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the therapeutical effects of salvianolic acid B (Sal B) on myocardial infarction(MI) in dogs. METHODS : The models of myocardial infarction were produced by ligation of the left anterior descending (LAD) coronary artery in the anaesthetized dogs. The extent of myocardial ischemia was detected by epicardial-electrocardiogram and the extent of infarction was determhled by N-BT staining method. The parameter of lactate dehydrogenase was determined in the serums of dogs. RESULTS : It was indicated that the adminstration of Sal B(1、3 and 10mg/kg) by the way of intravenous injection reduced the extent of myocardial infarction (N-ST) ( P
