Interference test in bacterial endotoxins detection of Shenmai Freeze-dried Powder Injection
- VernacularTitle:参麦冻干粉针剂中细菌内毒素检查干扰试验
- Author:
Hong GOU
;
Yifan CHENG
- Publication Type:Journal Article
- Keywords:
Shenmai Freeze-dried Powder Injection;
bacterial endotoxin test (BET);
interference test
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To prove the feasibility of bacterial endotoxin test (BET) in Shenmai Freeze-dried Powder Injection by interference test. Methods Interference primary screening test and interference test were conducted in BET of Shenmai Freeze-dried Powder Injection to detect whether the interference existed or not and to explore the method of removing the interference. Results There was inhibition on BET with 0.5 EU/mL tachypleus amebocyte lysate (TAL). Interference could be excluded by using 0.25 EU/mL TAL and diluting the samples. Conclusion It is feasible to use 0.25 EU/mL TAL or TAL with more sensitivity in BET of Shenmai Freeze-dried Powder Injection.
