Effects of resveratrol on proliferation and apoptosis of nasopharyngeal carcinoma cell line CNE-2Z
- VernacularTitle:白藜芦醇对鼻咽癌细胞株CNE-2Z增殖和凋亡的影响
- Author:
Xudong TANG
;
Keyuan ZHOU
;
Nan ZHAO
- Publication Type:Journal Article
- Keywords:
resveratrol (Res);
nasopharyngeal carcinoma;
proliferation;
apoptosis
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To investigate the effects of resveratrol (Res) on the proliferation and apoptosis of nasopharyngeal carcinoma cell line CNE-2Z. Methods IC 50 values were detected by MTT assay. The apoptosis was analyzed by flow cytometry (FCM), Hoechst 33258/PI fluorescence staining, and DNA agarose gel electrophoresis. Results After CNE-2Z cells were treated with different concentrations of Res for 24, 48, and 72 h, their IC 50 values were (109.2?7.5), (83.6?6.0), and (54.3?2.8) ?mol/L respectively (P
