Correlation of angiographic coronary atherosclerosis findings with plasma levels of von willebrand factor and ?-granule membrane protein
- VernacularTitle:冠状动脉粥样硬化病变与血浆血管性血友病因子和?颗粒膜蛋白水平的关系
- Author:
Yanhong ZHANG
;
Guoxian QI
;
Ningfu WANG
- Publication Type:Journal Article
- Keywords:
Coronary atheroslerosis;
Angiography;
von Willebrand factor;
?-granule membrane protein
- From:
Journal of Interventional Radiology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the angiographic coronary atheroslerosis findings with the plasma levels of von Willebrand factor (vWF) and ?-granule membrane protein (GMP-140). Methods 74 patients undergone selectrive coronary angiography (CAG) were divided into 3 groups based on plaque morphology, Group S(n=15), concentric or eccentric stenosis with smooth borders; Group C(n=37), eccentric stenosis with complex borders; Group N (n=22), CAG without coronary atheroslerosis. 37 patients in group C were divided into group Ⅰ (n=10, one-vessel involved CAD), group Ⅱ (n=12, two-vessel involved CAD) and group Ⅲ (n=15, three-vessel involved CAD) based on major epicardial coronary branches lesion. These 37 patients were divided into group x(n=21, ≤3 segments) and group y(n=16,≥4 segments) based on coronry stenotic segments. The plasma levels of vWF and GMP-140 were assayed by ELISA before angiography. Results (1)The plasma levels of vWF and GMP-140 in group C were significantly higher than those in group S(P
