The correlation between serum vascular endothelial growth factor expression after transcatheter arterial chemoembolization and the characteristic imaging features for human hepatocellular carcinoma: A clinical study
- VernacularTitle:经化疗栓塞治疗后肝细胞癌患者血清血管内皮生长因子与影像学特征的关系
- Author:
Zhengping XIONG
;
Shuren YANG
;
Zhaoyu LIANG
- Publication Type:Journal Article
- Keywords:
Hepatocellular carcinoma;
Vascular endothelial growth factor;
Embolization;
chemotherapy;
Imaging
- From:Journal of Interventional Radiology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prospectively evaluate changes in serum vascular endothelial growth factor (VEGF) levels in patients with hepatocellular carcinoma (HCC) before and after transcatheter arterial chemoembolization (TACE), and to investigate the association between serum VEGF levels and characters of imaging features. Methods Serum VEGF levels in 30 patients with HCC were measured on one day before TACE 3-4 days and 28-30 days after TACE, using quatitative sandwich enzyme-linked immunosorbent assay (ELISA R&D system). The occurrence of metastasis was assessed 6 months after TACE by CT (computed tomography) and DSA (digital subtraction angiography). Results (1) Serum VEGF levels had a tendency to increase in patients with the heterogenous uptake of iodine oil and those with portal vein invasion (P
