Protective Effects of Serum Contained Yixinyin on Cultured Beating myocardial Cells Infected with Coxsackie B_3 Virus in SD Rats
- VernacularTitle:益心饮血清对感染柯萨奇B_3病毒大鼠搏动心肌细胞的保护作用
- Author:
Xiao WEI
;
Zhifeng QIN
;
Pinkang WEI
;
Jianwen LIU
- Publication Type:Journal Article
- Keywords:
Yixinyin;
Myocarditis;
Sero- pharmacology;
Cell culture
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Yixinyin on viral myocarditis.Methods The beating myocardial cells were obtained from the ventricular myocardium of newborn Sparaque- Dawley (SD) rats and were incubated with Coxsackie B3 virus for 48 hours to establish the experimental model of viral myocarditis.With Yixinyin- contained serum added, the beating rate and survival rate of myocardial cells,and the activity of lactate dehydrogenase were measured at the 1st, 3rd and 5th day after infection. Results Serum contained Yixinyin can increase the beating rate and survival rate of the infected myocardial cells,and decrease the activity of lactate dehydrogenase significantly. Conclusion Serum contained Yixinyin has significant protective effect on myocardial cells infected with Coxsackie B3 virus in SD rats.
