Effects of microRNA and PI3K/AKT signaling pathway on cardiac development
10.3760/cma.j.issn.1673-4408.2012.03.004
- VernacularTitle:微小RNA与磷酸肌醇-3激酶／蛋白激酶B信号通路在心脏发育中的作用
- Author:
Zhangbin YU
- Publication Type:Journal Article
- Keywords:
MicroRNA;
Phosphoinosidde 3-kinase/protein kinase B;
Signaling pathway;
Cardiac development
- From:
International Journal of Pediatrics
2012;39(3):227-229,233
- CountryChina
- Language:Chinese
-
Abstract:
MiRNA can regulate cell proliferation and differentiation,and promote the development of organisms.Phosphoinositide 3-kinase/protein kinase B(PI3K/AKT) signaling pathway plays an important role in cell proliferation and differentiation,and also in organ and organization development.Studies concerning miRNA and PI3K/AKT signaling pathways in cardiac development and their relationship might help explain the pathogenesis of cardiac malformations and related diseases.
