A Case of Pulmonary Cryptococcosis with Non-Small Cell Lung Cancer in Idiopathic CD4+ T-Lymphocytopenia.
10.3349/ymj.2005.46.1.173
- Author:
In Seon AHN
1
;
Hee Gu KIM
;
Jeong Seon RYU
;
Lucia KIM
;
Seung Min KWAK
;
Hong Lyeol LEE
;
Yong Hwan YOON
;
Jae Hwa CHO
Author Information
1. Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. jaehwa. cho@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Idiopathic CD4 T-lymphocytopenia;
cryptococcosis;
lung cancer
- MeSH:
Aged;
CD4 Lymphocyte Count;
CD4-Positive T-Lymphocytes/*pathology;
Carcinoma, Non-Small-Cell Lung/*complications/immunology;
Cryptococcosis/*complications/immunology;
Humans;
Lung Neoplasms/*complications/immunology;
Lymphopenia/*complications/immunology;
Male
- From:Yonsei Medical Journal
2005;46(1):173-176
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cryptococcus neoformans commonly causes opportunistic infections in immunocompromised patients, especially in patients with AIDS. CD4+ T-lymphocytopenia in AIDS indicates an increased risk of opportunistic infection and a decline in immunological function. Idiopathic CD4 T-lymphocytopenia (ICL) is characterized by depletions in the CD4+ T-cell subsets, without evidence of HIV infection. Immunodeficiency can exist in the absence of laboratory evidence of HIV infection, and T-cell subsets should be evaluated in patients who present with unusual opportunistic infections. We report a case of pulmonary cryptococcosis and lung cancer in a patient with persistently low CD4+ cell counts, without evidence of HIV infection.
