Effects of Weiyanxiao on Basal Gastric-acid Secretion and Gastrin-induced Gastric-acid Secretion in Anesthetized Rats
- VernacularTitle:胃炎消对麻醉大鼠基础泌酸及胃泌素诱导泌酸的影响
- Author:
Qun DU
;
Xiumei WU
;
Rujun WANG
- Publication Type:Journal Article
- Keywords:
Weiyanxiao;
Gastric acid secretion;
Gastrin
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Effects of Weiyanxiao on basal gastric- acid secretion in anesthetized rats were investigated.Methods pH value of gastric perfusate in rat models of gastric perfusion were detected with a precise acidity meter to evaluated the effects of Weiyanxiao on basal gastric- acid secretion and gastrin- induced acid secretion.Results Small- dose Weiyanxiao (12.3 g/kg) had no significant influence on basal gastric- acid secretion and has slight inhibition on high- level gastric- acid secretion induced by gastrin ;large- dose Weiyanxiao (24.6g/kg) could restrain basal gastric- acid secretion (P
