Changes of ACTH, Cs and PRL Levels in Peripheral Blood From Patients With Active Systemic Lupus Erythematosus
- VernacularTitle:活动期SLE患者血中ACTH、Cs、PRL变化的研究
- Author:
Xiaofei WANG
;
Hui SHEN
;
Xiaoli ZHANG
;
Shuling BAI
- Publication Type:Journal Article
- From:
Journal of China Medical University
2001;30(2):137-138，140
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Our purpose was to investigate the changes of adrenocorticotropin (ACTH), Cortisol (Cs) and prolactin (PRL) levels in peripheral blood of patients with active systemie lupus erythematosus(SLE). Methods： Radioimmunoassy. Results： Active SLE patients had a low level of ACTH,Cs in peak phase and a high level of PRL. Consequentaly, the ratio of PRL/Cs increased, which was positively correlative to active index of SLE. Conclusion： Endogenetic secretion in sufficiency of glucocorticalsteroid and increase of PRL have important function in the initiation and development of SLE.
