THE EXPRESSION OF HOMOCYSTEINE INDUCED GENE IN NORMAL AND ABNORMAL HUMAN EMBRYONIC HEART
- VernacularTitle:同型半胱氨酸诱导基因在正常和畸形人胚心脏中的表达
- Author:
Guangming WANG
;
Shuhui ZHANG
;
Ying LI
;
Dangyu L
- Publication Type:Journal Article
- Keywords:
Homocysteine induced gene (HCY-2);
Expression;
Congenital malformation;
Human embryonic heart
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of homocysteine induced gene(HCY-2) in the normal and abnormal human embryonic heart. To research the roles of HCY-2 expressing protein in the human embryonic ventricular myocardial cell development and differentiation. Methods Immunohistochemistry and the technique of picture assay were used to detect HCY-2 expression in the normal and abnormal human embryonic heart. Results HCY-2 expresses during the development of human embryonic heart and mainly in the myocardial cells.The expression increases in the congenital malformation.Conclusion HCY-2 expression protein affects the development of human embryonic heart through affecting the myocardial cells proliferation and the abnormal expression has close relation to the congenital malformation.
