Concentration, purification and drying of Yuxianling Granules under aqueous extr action alcohol precipitation
- VernacularTitle:愈痫灵颗粒剂水提醇沉工艺中浓缩、纯化及干燥条件的研究
- Author:
Qun HE
;
Jingjing WANG
;
Biqing ZHAO
;
Guanghui YAO
;
Liang LIU
- Publication Type:Journal Article
- Keywords:
Yuxianling Granules;
aqueous extraction-alcohol pr ecipitation;
ferulic acid;
concentration;
purification;
drying
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To specify optimization of the concentration, purification and drying for prepar ati on of Yuxianling Grannles and decrease the dosage on condition that is retentive of potency in order to provide a basis for mass production. METHODS: The contents of ferulic acid and the amount of extract wer e used as marker, the optimium of concentration, purification and drying for pr eparation were selected by orthogonal design and contrast test during aqueous ex tract alcohol precipitation process. RESULTS: Condition was optimum of herb-to-extract ratio in the range of 0.5 ∶1, pr ecipitation with ethanol containing 40% water and drying temperature not to exce ed 60℃ . CONCLUSION: The highest yield of active priciples is obtained by c ondition above.
