Expression of CD147 in peripheral blood and joint fluid of patients with rheumatoid arthritis
- VernacularTitle:类风湿关节炎外周血与滑液细胞CD147分子表达的研究
- Author:
Jin DING
;
Ping ZHU
;
Chunmei FAN
- Publication Type:Journal Article
- Keywords:
Cell adhesion molecules;
CD147;
Arthritis,rheumatoid;
Lymphocytes;
Monocytes;
Neutrophils
- From:
Chinese Journal of Rheumatology
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the source of CD147 expressing cells in joint and its corelation with rheumatoid arthritis (RA),and to study the expression of CD147 on different cells of peripheral blood and joint fluid of RA patients and normal health controls.Methods The expression rate and intensity of CD147 on lymphocyte (CD3 +T),monocyte (CD14 + Mo) and neutrophils (N) of 10 active RA patients before and after treatment and 10 normal health controls′ peripheral blood and synovial fluid were studied by bicolor immunofluorescence flow cytometry.Results ① Compared with normal control,the expression intensity of CD147 on CD3 + T and CD14 + Mo were higher (P
