Clinical application in the therapy of rheumatoid arthritis with Technetium ~(99m)Tc methylenediphosphona-te injection
- VernacularTitle:~(99m)Tc-亚甲基二膦酸盐的临床新应用
- Author:
Nanping YANG
;
Chuan ZUO
;
Yongtao CHEN
;
Jiangtao LI
;
Ling WANG
- Publication Type:Journal Article
- Keywords:
Arthritis,rheumatoid;
Technetium Tc 99m medronate;
Treatment outcome
- From:
Chinese Journal of Rheumatology
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of Technetium 99m Tc methylenediphos-phonate injection (Yunke) and various combination therapy on rheumatoid arthritis.Methods All 137 patients enrolled in trial group.Among them 67 patients received Technetium 99m Tc methylenediphosphonate alone,42 patients received combination therapy with methotrexate and mobik and 28 patients received calcium orally meanwhile.Clinical manifestations and lab markers were observed carefully.Results The conditions of 67 patients receiving Technetium 99m Tc methylenediphosphonate alone were improved,42 patients received combination therapy had better effect and 28 patients in middle and old-age taking calcium orally simultaneously showed superiority in remission of rest pain and descent of ESR.Conclusion Technetium 99m Tc methylenediphosphonate is an effective and safe drug in the treatment of rheumatoid arthritis.Results is suggest calcium be taken in the same time.
