An experimental study of interventional therapy by direct puncture for the treatment of hormone-induced necrosis of femoral head
- VernacularTitle:直接穿刺介入治疗激素性股骨头坏死的实验研究
- Author:
Xingcan CHEN
;
Jingqing YU
;
Xiaoxiang ZHENG
- Publication Type:Journal Article
- Keywords:
Animal, experiment;
Interventional radiology;
Femoral head necrosis
- From:
Journal of Interventional Radiology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of interventional therapy by direct puncture for the treatment of avascular necrosis of the femoral head. Methods 24 experimental rabbits were undertaken and divided randomly into 3 groups, B, C groups as the models of hormone induced necrosis of femoral head, and A group as the control one. B group was followed up later with interventional therapy by direct puncture. Thromolytic agents, drugs improving microcirculation, and repairing bone tissue were infused directly into the femoral head; and then microscopic observations were conducted to study the pathology. Results The results showed: in group B, the number of vacant bony lacunae in femoral head, the average diameter of fat cells in marrow cavity and the number of blood vessel in subchondral areas showed significant improvement, approaching group A. Conclusions Treatment of femoral head necrosis through interventional method of direct puncture has commenced a solid foundation for clinical therapy.
