Effect of trimetazidine on cardiac systolic and diastolic function in patients with chronic congestive heart failure due to coronary artery disease
- VernacularTitle:曲美他嗪对冠心病心力衰竭患者心脏收缩和舒张功能的影响
- Author:
Dong LIU
- Publication Type:Journal Article
- Keywords:
Trimetazidine;
Coronary artery disease;
Heart failure;
Cardiac function
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of trimetazidine on cardiac systolic and diastolic function in patients with chronic congestive heart failure due to coronary artery disease.Methods:45 patients with chronic congestive heart failure due to coronary artery disease were divided into two groups,23 patients in trimetazidine group and 22 in placebo-control group.The echocardiogram indices of cardiac function of patients in two groups-SV,CO,CI,LVEF,VA,VE and VA/VE were measured before and after treatment.Results:The indexes SV,CO,CI and LVEF were significantly higher in trimetazidine group than those in control group(P0.05).Conclusion:Trimetazidine can improve systolic function of ischemic heart by improving the energy metabolism of ischemic heart.
