Study on the quality specification of Zanglian Pill
- VernacularTitle:脏连丸质量标准研究
- Author:
Zuqing LU
;
Shen JI
- Publication Type:Journal Article
- Keywords:
Zanglian Pill;
Quality eontrol;
Baicalin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(4):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the quality specification of Zanglian Pill. Methods Rhizoma coptidia,fructus sophorae and flos sophorae were identified by TLC. Radix scuteUariae was determined by HPLC. Intersit Cas column was used with the mobile phase of 2 % acetic acid-methanol(45:55 ), at the detection wavelength of 280nm.Results The calibration curve was linear in the range of 0. 0434~4.34 μg. The average recovery rate of baiealin was 99.2 % with RSD of 1.10 %. The TLC spots developed were fairly clear, and the blank test showed no interference. Conclusion The method developed is simple and accurate with a good reproducibility,and the method can be used for the quality control of Zanglian Pill.