Study on immune reconstruction of patients with advanced gastric cancer treated by autologous peripheral blood stem cells following chemotherapy
- VernacularTitle:自体干细胞移植对晚期胃癌患者化疗后免疫重建作用的研究
- Author:
Jinshui ZHU
;
Li ZHU
;
Long WANG
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Autologous peripheral blood stem cell transplantation;
Arterial chemotherapy;
TNM stage;
Cytokines
- From:
Chinese Journal of Digestion
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the immune reconstruction of patients with advanced gastric cancer treated by autologous peripheral blood stem cells following chemotherapy. Methods 54 patients with advanced stage of gastric cancer were accepted arterial chemotherapy under the guidance of DSA with the regimen of high dosage of EAP (VP16 100 mg/m 2, topmycine60 mg/m 2 and carplatine200 mg/m 2). Among them 20 patients underwent autologous peripheral blood stem cell transplantation after 48 hours of the chemothrapy. Results Effective rate of EAP arterial chemotherapy combined with autologous peripheral blood stem cell transplantation was up to 85.0% (17/20) in advanced gastric cancer, 29.3% (10/34) in control group ( P
