Changes of1HMRS and blood flow dynamics in acute cerebral infarction
- VernacularTitle:通过~1H磁共振波谱和经颅多普勒超声观察急性脑梗死患者早期代谢物及血流动力学的变化
- Author:
Huagang LI
;
Junjian ZHANG
;
Jian JIANG
;
Yumin LIU
- Publication Type:Journal Article
- Keywords:
Acute cerebral infarction;
Magnetic res onance spectroscopy;
Transcranial Doppler ultrasound;
Metabolite
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To get more diagnostic informa ti on from the acute cerebral infarct, We used1HMRS and TCD to investigate the r elationship between the metabolites in the infarct, the infarct volume, blood f low velocity and blood flow to the infarct, and the clinical neurologic deficit. MethodsFifteen patients with acute cerebral infarct underwent1HMRS and TCD examinations. Clinical neurologic deficit score was c ollected from every patient record at the time of the1HMRS and TCD study. Inf arct volume (V/ml) was determined with machine software automatically. A PRESS a cquisition was used for1HMRS. The peak areas of N,Lac,Cr,Cho in the lesi on region were compared with those in the contralateral side. TCD was performed for measuring Vs, Vm of encephalic blood vessels on both sides, and the responsi ble cerebral blood flow was estimated by Vs. ResultsT here were significant decrease of N,Cr,Vm and ECBF in the lesion region when c ompared with the contralateral side( P