Orlistal combined with low calorie diet in the treatment of obesity with non-alcoholic steatohepatitis
- VernacularTitle:奥利司他结合低热量饮食治疗肥胖伴非酒精性脂肪性肝病的临床研究
- Author:
Dekai QIU
;
Zhuping FAN
;
Weifen XIE
- Publication Type:Journal Article
- Keywords:
Obesity;
Non-alcoholic fatty liver disease;
Orlistat;
Low calorie diet;
Safety
- From:
Chinese Journal of Digestion
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of orlistat combined with low calorie diet in the treatment of obesity with non-alcoholic fatty liver disease. Methods Orlistat 120 mg, three times a day, combined with low calorie diet for a cause of 24 weeks, were given to the 60 non-alcoholic fatty liver disease (NAFLD) patients whose body mass index (BMI) were between 27 and 40. Results ①The percentage of mean weight loss and mean decreased BMI were both (10.76? 4.52 )% of their initinal weight at 24 weeks treatment. ②ALT, AST, GGT and total bilirubin was significantly decreased ( P
