The study of 24-hours blood pressure variability and the intervention with enalapril in essential hypertensives
- VernacularTitle:高血压病人24小时血压变异性及依那普利的干预影响
- Author:
Yong LIU
;
Tao YANG
- Publication Type:Journal Article
- Keywords:
Essential hypertension;
ABPM;
Blood pressure variability;
Enalapril
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study 24-hour blood pressure variability (BPV) in essential hypertensives(EH) and to observe the effects of enalapril on BPV in the patients. Methods: BPV were evaluated in 132 EH patients (EH Ⅰ-Ⅱ group 90, EH Ⅲ group 42) using ambulatory blood pressure monitoring, and compared with 60 normal controls.45 EH Ⅰ-Ⅱ patients were treated with enalapril for 4 weeks by randomized single-blind study.The BPV were measured before and after treatment. Results: The SBPV and MAPV during 24-hour period, daytime or nighttime were significantly higher both EH Ⅰ-Ⅱ and EH Ⅲ than control group ( P 0.05).Conclusion:There was a significant increase in BPV(especially in SBPV) and in particular EH Ⅲ group than control group There was no effect in BPV with EH Ⅰ-Ⅱ group by enalapril treatment for 4 weeks.
