Antipyretic and Analgesic Effects of Rhizoma Zingiberis Alcoholic Extract and Its In-vitro Antibacterial Actions
- VernacularTitle:干姜乙醇提取物解热镇痛及体外抑菌作用研究
- Author:
Meng WANG
;
Hongmei QIAN
;
Jiandan SU
- Publication Type:Journal Article
- Keywords:
@ Rhizoma Zingiberis Alcoholic Extract/pharmacology;
Inflammatory/TCD therapy;
@antipyretic and analgesic effects;
bacteria/drug effect;
Disease models, animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the anti-inflammatory, antipyretic and analgesic effects of Rhizoma Zingiberis alcoholic Extract (RZE) and to explore its in-vitro antibacterial actions. Methods Auricular swelling method in mice, typhoid and paratyphoid vaccines-induced fever in rabbits and bodytwisting test in mice were used respectively to observe the anti-inflammatory, antipyretic and analgesic effects of RZE. Results RZE could inhibit xylene-induced auricular swelling and bodytwisting response reaction induced by acetic acid in mice; RZE also reduce the vaccines-induced fever in rabbits. MIC of RZE for 8 bacterial strains ranged 13.5 mg/mL to 432 mg/mL. Conclusion RZE has a significant anti-inflammatory, antipyretic and analgesic effects and exert in-vitro antibacterial action.
