Effect of Yiqi Fuzhi Granule in Improving Learning and Memory of Rats with Multi-infarct Dementia
- VernacularTitle:益气复智颗粒对多梗塞性痴呆模型大鼠学习记忆能力的改善作用
- Author:
Jianying ZHOU
;
Chunhua JIANG
;
Mingyan WANG
- Publication Type:Journal Article
- Keywords:
@ Multi-infarct Dementia/TCD therapy;
@Yiqi fuzhi Granule/pharmacology;
Disease models, animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the eitect oi Yiqi Fuzhi Granule in improving learning and memory of rats with mul- ti-infarct dementia (MID). Methods MID rat models were established by embolus injection through the common carotid artery. Effects of Yiqi Fuzhi Granule(24. 84 g/kg, 12.42 g/kg, 6.21 g/kg, ig)on rat learning and memory and cerebral structure were observed. Results Yiqi Fuzhi Granule could obviously increase the scores of maze test and protect cerebral tissue from damage of multi-infarction rats. Conclusion Yiqi Fuzhi Granule has good effect in improving intellect and treating dementia.