Determination of Ferulic Acid in Bogu Pill by HPLC
- VernacularTitle:HPLC法测定驳骨丸中阿魏酸的含量
- Author:
Qixun TANG
;
Yanling LI
;
Rongzhen PENG
;
Yi WU
- Publication Type:Journal Article
- Keywords:
@ Bogu pill/chemistry;
Ferulic acid/analysis;
Chromatography, high pressure liquid
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for the content determination of ferulic acid in Bogu Pill(BP). Methods Ferulic acid was obtained by ultrasonic extraction at room temperature and detected by HPLC. HPLC was performed with ODS chromatographic column, methanol-acetonitrile-1%acetic acid(15: 15: 70) as mobile phase and detection wavelength at 323 nm. Results The linearity of ferulic acid was in the range of 0.56 ?g～11.20 ?g/mL(r=0.9996), and the average recovery was 100.26%, RSD=1.48%. Conclusion This method was efficient and can be used for the quality control of BP.
