STUDY ON GENE EXPRESSION AND REGULATION OF AROMATASE IN MALIGNANT GLIOMA CELL LINE SHG-44
- VernacularTitle:芳香化酶在胶质母细胞瘤细胞系SHG-44细胞中的表达及调控
- Author:
Lan XIAO
;
Wenqin CAI
- Publication Type:Journal Article
- Keywords:
Aromatase;
Glioma cell line SHG-44;
Gene expression
- From:
Acta Anatomica Sinica
2002;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the gene expression of aromatase and estrogen receptor (ER-?) in malignant glioma cell line SHG-44. Methods Cell culture, immunocytochemistry, in situ hybridization and RT-PCR techniques were used. Results Aromatase and estrogen receptor gene expressions were detected in SHG-44 cells.The aromatase gene in these cells was expressed by means of the multi promoters (1^3, 1^4 and P Ⅱ).Conclusion It may provide some new data for the hormone regulation in carcinoma of nerve system.
