Pathological Features, Secretion and Helicobacter Pylori Infectionin Gastric Mucosa of Chronic Superficial Gastritis withSpleen-Stomach and Damp-Heat Syndrome
- VernacularTitle:慢性浅表性胃炎脾胃湿热证胃粘膜病理、幽门螺杆菌感染及胃粘膜分泌特点
- Author:
Chunxia FENG
;
Shaoxian LAO
;
Zhixin HUANG
;
Fusheng ZHOU
- Publication Type:Journal Article
- Keywords:
GASTRITIS/physiopathology;
GASTRIC MUCOSA/pathology;
SPLEEN-STOMACH DAMP-HEAT;
INTERLEUKIN-8/analysis;
TUMOR NECROSIS FACTOR/analysis;
IMMUNOGLOBULIN A/analysis;
HELICOBACTER INFECTIONS
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the pathological features, secretion of interleukin-8 (IL - 8), tumor necrosis factor alpha (TNF-?) and secretory immunoglobulin A (sIgA) and helicobacter pylori (HP) infection in gastric mucosa (GM) of chronic superficial gastritis with spleen-stomach and damp-heat syndrome (SSDHS) and to explore their correlations. [Methods] Fifty-five cases of chronic superficial gastritis included 35 cases of SSDHS (Group A) and 20 cases of spleen-deficiency syndrome (Group B). Fifteen asymptomatic volunteers served as normal control group (Group C). Pathological changes, HP infection rate, levels of IL - 8, TNF -? and sIgA in GM were observed. [Results] HP infection rate was higher and inflammatory change was more obvious in Group A than those in Group B and Group C (P 0.05). [Conclusion] Gastric mucosa of chronic superficial gastritis with SSDHS presents inflammatory changes, which is related with the increase of IL - 8 and TNF -? secretion and the decrease of sIgA, and HP infection may be one of the factors inducing and enhancing the pathological changes.
