Primary analysis of family investigation of congenital heart disease in Chongqing
- VernacularTitle:重庆地区先天性心脏病家系筛查的初步分析
- Author:
Yuan CHEN
- Publication Type:Journal Article
- Keywords:
Congenital heart disease;
Heredity;
Family investigation
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the family history of congenital heart disease (CHD) in Chogqing for studying the genetic relation of CHD families. Methods:The materials were collected from the population survey about families with more than one members being CHD patients. Map pedigrees for high-risk families were made. The probands and the first and second grade relatives were asked to fill in questionnaires and the high-risk families were analyzed. Results:In the survey of 4387 families, there were 21 high-risk families in which the disease types of the relative patients were inconsistent with those of the probands, the coincidence being 33.33%(7/121).The incidence rates of the first and second grade relatives were 16.49%(16/78),1.89%(5/265) respectively and their difference was significant ( ? 2=27.73, P
