Expression of P27kipl protein and cyclin E protein in renal cell carcinoma
- VernacularTitle:P27kipl和cyclin E在肾细胞癌中表达的研究
- Author:
Jun SHEN
- Publication Type:Journal Article
- Keywords:
Renal carcinoma;
P27kipl;
Cyclin E;
Immunohistochemistry
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expressions of P27kipl (P27) protein and cyclin E protein in human renal cell carcinoma and in paracarcinoma kidney cortex tissue,and to explore the correlation of these protein expressions with biological behavior of tumors.Methods:P27 and cyclin E expressions were studied in formalin-fixed,paraffin-embedded sections of renal cell carcinoma and in paracarcinoma kidney cortex tissue by means of a specific and sensitive immunohistochemical S-P assay.Results:The positive rates of P27 protein and cyclin E protein in renal cell carcinoma were significantly higher than those in paracarcinoma kidney cortex tissues ( P
