Effect of Dan Sen on gastric mucosal Na~+-K~+-ATPase activity and gastric transmucosal potential difference in rats during severe intraperitoneal infection
- VernacularTitle:丹参注射液对腹腔感染状态下胃粘膜Na~+-K~+-ATPase活性和电位差的影响
- Author:
Mao ZHANG
- Publication Type:Journal Article
- Keywords:
Intraperitoneal infection;
Na +-K +-ATPase;
GTPD;
Dan Sen
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of Dan Sen on gastric mucosal Na +-K +-ATPase activity and gastric transmucosal potential difference in rats during severe intraperitoneal infection.Methods:The intraperitoneally infected rat model was established by cecal ligation and puncture(CLP).Assay of Na +-K +-ATPase activity in gastric mucosal tissue was conducted by biochemistry method.The electric-physiological recorder meter was used to measure gastric mucosal potential difference.Results:The activity of Na +-K +-ATPase markedly decreased in infected group at 3h after perforation,compared with the control group ( P
